49ers 48, Colts 27
| 1 | 2 | 3 | 4 | T | |
|---|---|---|---|---|---|
| SF11-4 | 14 | 10 | 10 | 14 | 48 |
| IND8-7 | 7 | 10 | 3 | 7 | 27 |
Scoring
First Quarter
IND — Alec Pierce 20 Yd pass from Philip Rivers (Blake Grupe Kick), 10:31(0-7)
SF — Demarcus Robinson 22 Yd pass from Brock Purdy (Eddy Pineiro Kick), 7:14(7-7)
SF — Christian McCaffrey 2 Yd pass from Brock Purdy (Eddy Pineiro Kick), 4:33(14-7)
Second Quarter
IND — Alec Pierce 16 Yd pass from Philip Rivers (Blake Grupe Kick), 14:15(14-14)
SF — George Kittle 11 Yd pass from Brock Purdy (Eddy Pineiro Kick), 9:36(21-14)
SF — Eddy Pineiro 25 Yd Field Goal , 1:51(24-14)
IND — Blake Grupe 39 Yd Field Goal, 0:17(24-17)
Third Quarter
SF — Jauan Jennings 3 Yd pass from Brock Purdy (Eddy Pineiro Kick), 10:58(31-17)
IND — Blake Grupe 51 Yd Field Goal, 8:16(31-20)
SF — Eddy Pineiro 38 Yd Field Goal , 4:02(34-20)
Fourth Quarter
IND — Jonathan Taylor 1 Yd Rush (Blake Grupe Kick), 12:41(34-27)
SF — Christian McCaffrey 9 Yd pass from Brock Purdy (Eddy Pineiro Kick), 7:37(41-27)
SF — Dee Winters 74 Yd Interception Return (Eddy Pineiro Kick), 3:26(48-27)
Team Stats
| SF | IND | |
|---|---|---|
| First downs | 28 | 19 |
| Total yards | 440 | 312 |
| Rushing yards | 145 | 58 |
| Passing yards | 295 | 254 |
| 3rd down eff. | 7-11 | 5-10 |
| 4th down eff. | 1-1 | 0-1 |
| Penalties | 2-36 | 6-45 |
| Turnovers | 1 | 2 |
| Possession | 33:05 | 26:55 |
Lucas Oil Stadium. A—66,265.